The calcium-sensing receptor in health and disease

G Díaz-Soto, A Rocher, C García-Rodríguez… - … review of cell and …, 2016 - Elsevier
… , the skeleton acts as a major reservoir of calcium and can … 2+ -dependent inactivation of
TRPV6. A similar mechanism … the use of calcilytics to efficiently slow down the symptoms of AD, …

L-Amino Acids Promote Calcitonin Release via a Calcium-Sensing Receptor: Gq/11-Mediated Pathway in Human C-Cells

H Mun, KM Leach, AD Conigrave - Endocrinology, 2019 - academic.oup.com
… on calcitonin-secreting thyroid C-cells and thereby induce Ca … basal Ca 2+ o concentration
of 0.5 mM, we observed a slow, … 2, have been linked to inactivating and activating mutations of …

[HTML][HTML] Calcium-sensing receptor: A new target for therapy of diarrhea

SX Cheng - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
… Secretagogue-induced increases in cellular accumulation of … ] and are effective in slow down
of the gastrointestinal transit … associated with calcitonin-secreting medullary thyroid cancer[…

[HTML][HTML] Calcium-sensing receptor: a key target for extracellular calcium signaling in neurons

BL Jones, SM Smith - Frontiers in physiology, 2016 - frontiersin.org
… changes in extracellular calcium to alter cellular excitability have been … of extracellular
calcium signaling are suggested by work … These relatively slow kinetics indicate the CaSR-NSCC …

[图书][B] The calcium-sensing receptor as a mineral sensor

PP Centeno - 2019 - search.proquest.com
… The work discussed in this thesis concludes my PhD in … gland, bone, calcitonin-secreting
thyroidal cells, and kidney, but … eral ions and ensuring that calcium-phosphate product (Ca x P) …

[HTML][HTML] Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial …

X Wang, J Lundblad, SM Smith - PloS one, 2022 - journals.plos.org
cell membrane and still able to detect changes in [Ca 2+ ] o . We tested this hypothesis by
measuring intracellular [Ca 2+ ] in HEK cells … and then decreased slowly during the application …

15 BIOCHEMICAL MARKERS OF BONE METABOLISM

KM Klemm, MJ Klein - … by Laboratory Methods: First South Asia …, 2016 - books.google.com
… Arsenazo III reacts with calcium to form a calcium-indicator … parathyroid glands, the
calcitonin-secreting cells of the thyroid… C cells (parafollicular cells) of the thyroid gland and acts on …

Ca2+ Channel Blockers

J Striessnig, NJ Ortner - Encyclopedia of Molecular Pharmacology, 2022 - Springer
… Once the cell repolarizes, inactivated channels return to the … Instead, DHPs with slower
onset and longer duration of action (… calcium levels, such as the thyroidal calcitonin-secreting C-…

Ca2+-Sensing Receptor (CaSR)

G Valenti - Encyclopedia of Molecular Pharmacology, 2022 - Springer
… Once the cell repolarizes, inactivated channels return to the … Instead, DHPs with slower
onset and longer duration of action (… calcium levels, such as the thyroidal calcitonin-secreting C-…

Hormone secreting gastro-entero-pancreatic neuroendocrine neoplasias (GEP-NEN): When to consider, how to diagnose?

C Fottner, M Ferrata, MM Weber - Reviews in Endocrine and Metabolic …, 2017 - Springer
… have a favorable prognosis due to a slow tumor growth, mean 5-… cause of beta cell hypertrophy
is largely unknown, the beta cell … Only few patients with calcitonin-secreting tumors show …